NFL Week 3 picks: Rams defeat favored Eagles; Chargers go to 3-0

Kansas City Chiefs quarterback Patrick Mahomes runs with the ball against the Philadelphia Eagles on Sept. 14.

Kansas City Chiefs quarterback Patrick Mahomes runs with the ball against the Philadelphia Eagles on Sept. 14.

(Ed Zurga / Associated Press)

Sunday, 5:20 p.m. TV: NBC, Peacock.

Line: Chiefs by 5½. O/U: 44½.

The Giants made it very interesting against Dallas, but it’s highly unlikely Patrick Mahomes loses a fourth game in a row here. Kansas City’s defense is far better, although the Chiefs are thin at receiver.

Pick: Chiefs 24, Giants 13